Gut Microbiome And Epigenetic Changes Under Acute Stress

The gut microbiome is well recognised to play a pivotal role in human health and performance. The gut microbiome exerts its effects by means of metabolites, likely accompanied with epigenetic changes. Among various species, crocodiles are well known for their “hardiness” and ability to achieve longevity while surviving under stressful conditions. We speculated that their microbial gut flora produces substances contributing to their “performance” and “wellbeing” and “longevity”. Previously, we have evaluated gut bacteria of crocodiles and identified two gut bacterial isolates which produce several metabolites, that likely contribute to their longevity and ability to endure stressful environments.