An integrated decision support framework for resilient vaccine supply chain network design

Designing resilient supply chain networks for vaccine development and distribution requires reliable and robust infrastructure. This stud develops a novel two-stage decision support framework for configuring multi-echelon Supply Chain Networks (SCNs), resilient supplier selection, and order allocation under uncertainty. Resilient supplier selection is done using a hybrid Multi-Criteria Decision-Making (MCDM) approach based on Best-Worst Method (BWM), Weighted Aggregated Sum Product Assessment (WASPAS), and Type-2 Neutrosophic Fuzzy Numbers (T2NN). A robust multi-objective optimization model is then built for order allocation considering resiliency scores, reliability of facilities, and uncertain supply and demand. The objectives are to minimize the total cost of SCN design, maximize the resiliency score, and maximize the reliability of SC, respectively. A Non-dominated Sorting Genetic Algorithm II (NSGA-II) is developed to tackle the problem on large scales, tuned by the Taguchi design technique. The NSGA-II solution is compared to the ε-constraint and Multi-objective Particle Swarm Optimization (MOPSO) solutions using test problems. We demonstrate the superiority of the suggested NSGA-II method over the two competing methods according to five performance metrics. A case study is then investigated to illustrate the applicability and effectiveness of the offered methodology for COVID-19 vaccine distribution in a developing country. It is revealed that the models and algorithms can treat the problem optimally, such that Germany is the main source (approximately 25.61%) while India does not contribute to the supply of vaccines.