Antibacterial and anthelmintic effect of the combination of pomegranate peel and olive leaf extracts

Pomegranate peel and olive leaf are known to have antibacterial activity. These two plants have been studied in various studies. However, there is no study on the synergistic effect of these two plants. In this study, the antibacterial activity of a supplement containing pomegranate peel and olive leaf extracts against S. mutans and its antihelmintic activity against C. elegans were determined. Results obtained by the disk diffusion method and microdilution test are 12.5 mm and ≥ 1024 μg/ mL, respectively. Anthelmintic activity experiments revealed that the lifespan of worms was shortened as a result of the synergistic effect of the extracts. Our results revealed the synergistic effect of these two extracts against the microbes and possible helminths in the oral flora. Increasing antibiotic resistance has led researchers to work on the detection of new plant extracts and substances. It is aimed that this study on plant extracts will help future studies.