The importance of colposcopic biopsy in cervical smear pathologies colposcopic biopys in cervical screening

Aim: To evaluate the results of colposcopy-guided biopsy in patients diagnosed with low- and high-grade cervical intraepithelial neoplasia (CIN) identified by Pap smear test. Methods: A total of 102 patients with low- and high-grade CIN diagnosed by Pap smear test, who underwent colposcopy-guided biopsy in the gynecology and obstretrics outpatient clinics at Haseki Tranining and Research Hospital, were included in this retrospective study. Results: One hundred and two patients were included in our study. Colposcopy-guided biopsy results of patients with low-grade and high-grade CIN were as follows: acanthosis and chronic cervicitis-36 (50%) and five (16%), CIN I - 28 (38%) and nine (30%), and CIN II-III - 8 (11%) and 16 (53%), respectively. The specificity and sensitivity of colposcopy-guided biopsy in detecting CIN II-III in patients with high-grade CIN were 67% and 80%, respectively, and the positive predictive value was 50%. Conclusion: Considering the fact that smear is a screening test, the diagnosis of low-grade and high-grade CIN should be confirmed with colposcopy-guided biopsy.